Colonization of skin with Staphylococcus aureus is in most cases non-symptomatic, but the pathogen can cause infections when the skin’s protective barrier function is breached. Staphylococcus infections are often associated with skin diseases as atopic dermatitis (eczema), carbuncle, cellulitis, rosacea, psoriasis, diaper rash, impetigo and wounds.
Human Staphylococcus skin infections are especially problematic in relation to atopic dermatitis
Staphylococcus aureus is known to colonize the skin of 70-80% of patients with atopic dermatitis, it is found on lesioned as well as non lesioned skin, and contribute to inflammation and flares of disease. Skin infection with S. aureus is often treated with antibiotics, such as Fusidic acid or methicillin, however, treatment with antibiotics causes resistance of the bacteria and damages the skin microbiome.
Lactiplantibacillus plantarum LB244R® is a Gram positive lactic acid producing bacterium, specifically selected for its ability to inhibit the growth of pathogenic Staphylococcus aureus including Methicillin Resistant Staphylococcus aureus (MRSA) and the CC1 pathogen. CC1 is the commensal clonal type of resistant S. aureus associated with atopic dermatitis.